Oxygen-embedded quinoidal acene based semiconducting chromophore nanoprobe for amplified photoacoustic imaging

In this chapter, we summarize the advantages of photoacoustic imaging and the current methods of enhancing photoacoustic. We then provide detailed procedures for the synthesis and characterization of a photoacoustic imaging molecule, Nano(O-Nonacene)-PEG, developed in our research group. At the same time, we proved that the incorporation of Zn_0.4Fe_2.6O₄ can enhance the photoacoustic imaging effect of Nano(O-Nonacene)-PEG. This provides a new material for photoacoustic imaging to guide tumor treatment.