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Forensic Neuropathologic Phenotypes of Fungal Central Nervous System Infections: A Case Series
Gary Wu1, Ying Liu2, Elena Bulakhtina3
1From the Rush Medical College, Rush University, Chicago, IL.
The American Journal of Forensic Medicine and Pathology
|August 6, 2021
Summary
Fungal infections of the central nervous system (FI-CNS) are increasing and can affect anyone. This case series highlights diverse presentations of FI-CNS, emphasizing the need for early clinical suspicion to improve outcomes.
Area of Science:
- Neurology
- Infectious Diseases
- Mycology
Background:
- Fungal infections of the central nervous system (FI-CNS) are life-threatening, increasingly affecting both immunocompromised and immunocompetent individuals.
- The rising prevalence is linked to organ transplantation, HIV, and immunosuppressive therapies.
- FI-CNS often originate from extraneural sites and are caused by molds, dimorphic fungi, or yeasts.
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