Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two-Stage Multiple Test Procedures Controlling False Discovery Rate With Auxiliary Variable and Their Application to Set4 <math><semantics><mi>Δ</mi> <annotation>$\Delta$</annotation></semantics></math> Mutant Data.

Biometrical journal. Biometrische Zeitschrift·2026
Same author

3D nanoprinting of embryo microinjection needles with anti-clogging features.

Microsystems & nanoengineering·2025
Same author

Behavioral Health Status after Globe Removal in United States Service Members.

Ophthalmology·2025
Same author

Characterization of Mild Traumatic Brain Injury Cohort With Photophobia From the Defense and Veterans Eye Injury and Vision Registry.

Military medicine·2024
Same author

Optometric Brain Injury Curriculum in Federal Residency Training Programs: A Consensus Report.

Military medicine·2023
Same author

Set4 regulates stress response genes and coordinates histone deacetylases within yeast subtelomeres.

Life science alliance·2021
Same journal

Comparison of neutralization and disinfection kinetics in povidone iodine- and hydrogen peroxide-based soft contact lens care solutions.

Optometry and vision science : official publication of the American Academy of Optometry·2026
Same journal

Agreement between ganglion cell-inner plexiform layer metrics from widefield optical coherence tomography and Goldmann II, III, and V in glaucoma.

Optometry and vision science : official publication of the American Academy of Optometry·2026
Same journal

Repeatability of SpotChecks contrast sensitivity test in macular disease.

Optometry and vision science : official publication of the American Academy of Optometry·2026
Same journal

Reflections on emerging therapies for inherited retinal diseases following a community education event: A qualitative exploration.

Optometry and vision science : official publication of the American Academy of Optometry·2026
Same journal

Optical myopia control interventions: Evaluation of methods and success in a real-world population.

Optometry and vision science : official publication of the American Academy of Optometry·2026
Same journal

Influence of corneal endothelial cell density after penetrating keratoplasty on contact lens induced corneal swelling.

Optometry and vision science : official publication of the American Academy of Optometry·2026
See all related articles

Related Experiment Video

Updated: Oct 25, 2025

Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope
08:25

Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope

Published on: April 21, 2023

1.3K

Photophobia Associated with Traumatic Brain Injury: A Systematic Review and Meta-analysis.

Natalya Merezhinskaya1, Rita K Mallia1, DoHwan Park2

  • 1Department of Defense/Veterans Affairs Vision Center of Excellence, Bethesda, Maryland.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|August 6, 2021
PubMed
Summary
This summary is machine-generated.

Photophobia is common after traumatic brain injury (TBI), affecting over 30% initially. While it often improves within 3 months, persistent symptoms lasting up to a year occur in some TBI patients.

More Related Videos

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy
04:02

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Published on: November 29, 2024

1.3K
Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging
11:14

Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging

Published on: April 6, 2014

12.6K

Related Experiment Videos

Last Updated: Oct 25, 2025

Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope
08:25

Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope

Published on: April 21, 2023

1.3K
Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy
04:02

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Published on: November 29, 2024

1.3K
Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging
11:14

Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging

Published on: April 6, 2014

12.6K

Area of Science:

  • Neurology
  • Ophthalmology
  • Public Health

Background:

  • Photophobia is a common and potentially debilitating symptom following traumatic brain injury (TBI).
  • Understanding the prevalence and temporal course of photophobia post-TBI is crucial for patient management and research.

Purpose of the Study:

  • To systematically review and meta-analyze the existing literature to determine the prevalence and relative risk of photophobia in patients with TBI.
  • To identify factors influencing photophobia prevalence after TBI.

Main Methods:

  • A systematic literature search was conducted across PubMed, EMBASE, and Cochrane Library.
  • Meta-regression analyses using a generalized linear mixed model were employed to assess prevalence and heterogeneity.
  • Included studies reported photophobia prevalence in TBI patients of any age.

Main Results:

  • Seventy-five publications were included, revealing an initial photophobia prevalence of 30.46% at 1 week post-TBI.
  • Prevalence significantly decreased to 13.51% by 3 months but showed a plateau thereafter, with 14.85% at 12 months.
  • The risk ratio for photophobia was significantly higher in TBI patients compared to controls throughout the first year.

Conclusions:

  • Photophobia is a frequent complication of TBI, with a tendency to resolve within 3 months for many individuals.
  • However, persistent photophobia can last up to 12 months or longer in some TBI survivors.
  • Standardized measurement tools and diagnostic codes are needed to improve photophobia assessment and data collection in TBI.