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Protective effects of alpha-lipoic acid on hair cell damage in diabetic zebrafish model
Eunmi Kim1, Dong-Won Lee1, Hae-Chul Park1
1Department of Biomedical Sciences, College of Medicine, Korea University, Ansan 15355, Republic of Korea.
Molecular Genetics and Metabolism Reports
|August 6, 2021
Abstract:
Hearing impairment is one of the complications in diabetes mellitus; however, there are very few therapeutic studies on it. In this study, we investigated the protective effect of alpha-lipoic acid (ALA) on hearing loss in diabetic transgenic zebrafish and confirmed that ALA protects the loss of hair cells (HCs) caused by hyperglycemia. The data indicated that ALA has a protective effect on the damage to HCs in diabetic zebrafish.
