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Updated: Oct 25, 2025

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
Published on: February 7, 2016
Engineering with keratin: A functional material and a source of bioinspiration
Benjamin S Lazarus1, Charul Chadha2, Audrey Velasco-Hogan1
1Materials Science and Engineering Program, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, USA.
Abstract:
Keratin is a highly multifunctional biopolymer serving various roles in nature due to its diverse material properties, wide spectrum of structural designs, and impressive performance. Keratin-based materials are mechanically robust, thermally insulating, lightweight, capable of undergoing reversible adhesion through van der Waals forces, and exhibit structural coloration and hydrophobic surfaces. Thus, they have become templates for bioinspired designs and have even been applied as a functional material for biomedical applications and environmentally sustainable fiber-reinforced composites. This review aims to highlight keratin's remarkable capabilities as a biological component, a source of design inspiration, and an engineering material. We conclude with future directions for the exploration of keratinous materials.

