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[Automated synthesis of oligodeoxyribonucleotides. VI. Properties of segmental supports based on cellulose]
Bioorganicheskaia Khimiia
|October 1, 1987
Abstract:
The course of development of the rapid automated synthesis of oligodeoxyribonucleotides, various cellulose supports have been studied. Mild acid or aqueous ammonia treatment of Whatman or Filtrak paper disks is shown to improve characteristics of the supports, increasing the capacity in terms of the first immobilized nucleoside. New segmental supports based on cotton or flax were prepared and used successfully in automated synthesis of oligodeoxyribonucleotides on "Victoriya-2" synthesizer.