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Author Spotlight: Recent Advancements in Reoperative Foregut Surgery
04:14

Author Spotlight: Recent Advancements in Reoperative Foregut Surgery

Published on: September 22, 2023

654

Patient-Reported Outcome Measures and Clinical Outcomes in Children with Foregut Anomalies

Isabel I Sreeram1, Chantal A Ten Kate1, Joost van Rosmalen2,3

  • 1Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children's Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands.

Children (Basel, Switzerland)
|August 6, 2021
PubMed

Insights

Patient-reported outcome measures (PROMs) for health status and quality of life in children with foregut anomalies provide valuable insights. These measures, alongside clinical outcomes, offer a holistic view of a child's wellbeing.

Area of Science:

  • Pediatric Surgery
  • Value-Based Healthcare
  • Patient-Reported Outcomes

Background:

  • Chronic conditions in children necessitate value-based healthcare approaches.
  • Patient-reported outcome measures (PROMs) are crucial for value-based healthcare.
  • The relationship between PROMs and clinical outcomes in pediatric chronic diseases requires further investigation.

Purpose of the Study:

  • To assess the added value of self-reported PROMs for health status (HS) and quality of life (QoL) in the long-term follow-up of children with foregut anomalies.
  • To explore the association between PROMs and clinical outcomes in pediatric congenital diaphragmatic hernia (CDH), esophageal atresia (EA), and congenital lung malformations (CLM).

Main Methods:

  • Longitudinal follow-up data of 220 children (8-year-olds) with CDH, EA, or CLM were analyzed.
  • PROMs for HS and/or QoL were collected within a multidisciplinary program.
  • Multivariable linear regression analyses examined relationships between self-reported HS/QoL and categorized clinical outcomes.

Main Results:

  • Lower cognitive function was significantly associated with lower self-reported HS in children with CDH and EA.
  • Analysis was limited in children with CLM due to small case numbers.
  • HS, QoL, and clinical outcomes represent distinct facets of a child's wellbeing.

Conclusions:

  • Self-reported HS and QoL are important components of assessing long-term outcomes in children with foregut anomalies.
  • Simultaneous measurement of PROMs and clinical outcomes is recommended for a comprehensive understanding of child wellbeing.
  • Integrating PROMs into clinical decision-making can enhance the holistic care of children with chronic conditions.

Keywords:
clinical decision-makingcongenital diaphragmatic herniacongenital lung malformationsesophageal atresiavalue-based healthcare

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