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Office-Based Renal Tumor Biopsy: a Paradigm Change in the Management of a Small Renal Mass?
Roshan M Patel1, Zhamshid Okhunov2, Pengbo Jiang2
1Department of Urology, University of California, Orange, CA, USA. roshanmp@uci.edu.
Purpose Of Review:
The goal of this paper is to evaluate the use of an office-based renal mass biopsy (RMB), whose feasibility could represent a paradigm shift in clinical practice.
Recent Findings:
Despite the earlier diagnosis of patients with renal masses, the lack of evidence showing a reduction in cancer-specific mortality warrants an examination in treatment practices. RMB is underutilized when compared to biopsy practice for all other neoplasms in every other solid organ (except testis), and the majority of RMB performed are outsourced to interventional radiologists. Performing an ultrasound-guided, office-based RMB is safe, reproducible, and has a meaningful impact on management decisions. The use of percutaneous RMB in clinical practice is growing, and the use of RMB has meaningful impact on management decisions for renal masses. Incorporating ultrasound-guided biopsy of a renal mass into clinical practice is feasible, and in contemporary practice, the urologist has the skill set to perform the procedure reliably, with low morbidity, and with minimal patient discomfort.
Insights
Office-based renal mass biopsy (RMB) is safe and effective for diagnosing kidney tumors, potentially changing how these masses are managed. This procedure offers a reliable option for urologists, impacting clinical decisions.
Area of Science:
- Urology
- Diagnostic Imaging
- Nephrology
Background:
- Early diagnosis of renal masses is increasing, but evidence for reduced cancer-specific mortality is lacking.
- Renal mass biopsy (RMB) is underutilized compared to biopsies of other neoplasms.
- Most RMB procedures are currently performed by interventional radiologists.
Purpose of the Study:
- To evaluate the feasibility and impact of office-based renal mass biopsy (RMB).
- To assess the potential of RMB to shift clinical practice paradigms for renal mass management.
Main Methods:
- Performing ultrasound-guided, office-based RMB.
- Urologists utilizing their existing skill set for RMB procedures.
Main Results:
- Office-based RMB is safe, reproducible, and impacts management decisions for renal masses.
- The use of percutaneous RMB is growing in clinical practice.
- Urologists can perform RMB reliably with low morbidity and minimal patient discomfort.
Conclusions:
- Incorporating ultrasound-guided RMB into clinical practice is feasible.
- Office-based RMB offers a safe and effective option for urologists, influencing patient management.
- RMB has a meaningful impact on the clinical management of renal masses.
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