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Updated: Oct 25, 2025

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting
Ornela Bardhi1,2, Begonya Garcia-Zapirain1, Roberto Nuño-Solinis3
1eVida Laboratory, University of Deusto, Avenida Universidades 24, 48007 Bilbao, Spain.
This study analyzed breast and prostate cancer patient care pathways, finding that chemotherapy cycles, lifestyle, height, and weight influence treatment plans. Understanding these factors enables personalized patient care.
Area of Science:
- Oncology
- Medical Informatics
Background:
- Breast cancer (BCa) and prostate cancer (PCa) are leading causes of cancer incidence.
- Understanding patient care pathways is crucial for optimizing treatment strategies.
Purpose of the Study:
- To analyze BCa and PCa patient care pathways by examining treatment lines.
- To evaluate the association between treatment lines and patient demographic and lifestyle characteristics.
Main Methods:
- Utilized electronic health records (EHRs) and semi-structured interviews from 83 patients at Beacon Hospital (January-November 2018).
- Performed statistical analysis to identify variables impacting patient treatment plans.
Main Results:
- Chemotherapy cycles correlated with targeted therapy, endocrine therapy, and bisphosphonate use (indicating bone metastasis).
- Prostate cancer patients who were taller, heavier, and had a BMI > 25 received more chemotherapy.
- Lifestyle factors like diet and exercise in breast cancer patients were associated with surgical interventions; initial PSA levels predicted bisphosphonate treatment.
Conclusions:
- Chemotherapy cycles, lifestyle (BCa), height, and weight (PCa) are indicators for subsequent treatment plans.
- Identifying factors influencing care pathways supports a person-centered approach and care process redesign.
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