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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Guidelines and Experience Using Imaging Biomarker Explorer IBEX for Radiomics
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Intra-scan inter-tissue variability can help harmonize radiomics features in CT.

Hubert Beaumont1, Antoine Iannessi2, Jean Michel Cucchi3

  • 1Median Technologies, 06560, Valbonne, France. Hubert.beaumont@mediantechnologies.com.

European Radiology
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Repeatability of radiomics features in CT scans varies by tissue. Relative intra-scan measurements can enhance reliability for quantitative imaging and harmonization across sites.

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Area of Science:

  • Medical Imaging
  • Radiomics
  • Quantitative CT

Background:

  • Radiomics analysis in computed tomography (CT) is sensitive to variations in acquisition protocols.
  • Understanding the repeatability and variability of radiomics features is crucial for reliable quantitative imaging.

Purpose of the Study:

  • To assess the repeatability and relative intra-scan variability of radiomics features across different CT acquisition protocols.
  • To identify radiomics features suitable for improving tissue characterization and inter-site harmonization.

Main Methods:

  • Utilized CT scans from a radiomics phantom and unenhanced abdominal patient series.
  • Extracted 9 radiomics features, defining "tandems" as measurements of specific tissues by specific features.
  • Assessed variability sources (repetition, protocol, material, patient) and intra-scan correlation.

Main Results:

  • Radiomics feature repeatability is material-dependent; 56% of tandems were highly repeatable.
  • Histogram-derived radiomics showed lower repeatability; Gray Level Zone Length Matrix (GLZLM) and Gray Level Co-occurrence Matrix (GLCM) features showed high correlation.
  • Nearly 60% of relative radiomics measurements exceeded a 0.90 correlation coefficient, enabling paired measurements to improve material/tissue differentiation.

Conclusions:

  • Identified specific radiomics features with linearly correlated intra-scan measurements between tissues.
  • Relative intra-scan measurements offer a method to improve quantitative imaging reliability on CT.
  • Linear correlation property enhances tissue characterization and facilitates inter-site harmonization.