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Published on: May 17, 2018
Assessing unmet needs in advanced cancer patients: a systematic review of the development, content, and quality of
Ben Rimmer1, Lisa Crowe2, Adam Todd2,3
1Population Health Sciences Institute, Newcastle University, Newcastle University Centre for Cancer, Newcastle, England. ben.rimmer@newcastle.ac.uk.
Purpose:
Advances in treatment, including biological and precision therapies, mean that more people are living with advanced cancer. Supportive care needs likely change across the cancer journey. We systematically identified instruments available to assess unmet needs of advanced cancer patients and evaluated their development, content, and quality.
Methods:
Systematic searches of MEDLINE, CINAHL, Embase, PubMed, and PsycINFO were performed from inception to 11 January 2021. Independent reviewers screened for eligibility. Data was abstracted on instrument characteristics, development, and content. Quality appraisal included methodological and quality assessment, GRADE, feasibility, and interpretability, following consensus-based standards for the selection of health measurement instruments (COSMIN) guidelines.
Results:
Thirty studies reporting 24 instruments were identified. These were developed for general palliative patients (n = 2 instruments), advanced cancer (n = 8), and cancer irrespective of stage (n = 14). None focused on patients using biological or precision therapies. The most common item generation and reduction techniques were amending an existing instrument (n = 11 instruments) and factor analysis (n = 8), respectively. All instruments mapped to ≥ 5 of 11 unmet need dimensions, with Problems and Needs in Palliative Care (PNPC) and Psychosocial Needs Inventory (PNI) covering all 11. No instrument reported all of the COSMIN measurement properties, and methodological quality was variable.
Conclusions:
Many instruments are available to assess unmet needs in advanced cancer. There is extensive heterogeneity in their development, content, and quality.
Implications For Cancer Survivors:
Given the growth of precision and biological therapies, research needs to explore how these instruments perform in capturing the needs of people using such therapies.
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