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Updated: Oct 25, 2025

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
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Disseminated lymphangiomas as a cutaneous manifestation of Noonan syndrome

P Pérez-Feal1, N Moreiras-Arias1, C Buján-Bonino1

  • 1Departments of Dermatology, Clinical University, Hospital of Santiago de Compostela, A Coruña, Spain.

Clinical and Experimental Dermatology
|August 7, 2021
PubMed

Insights

Noonan syndrome can manifest as rare lymphangiomas. This case highlights disseminated cutaneous lymphangiomas and suggests oral rapamycin as a promising treatment for this condition.

Area of Science:

  • Dermatology
  • Genetics
  • Pediatrics

Background:

  • Lymphangioma, a rare vascular malformation, is an infrequent manifestation of Noonan syndrome.
  • Noonan syndrome is a genetic disorder with diverse clinical presentations.

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