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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

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Long term clinical outcomes of patients with ischemic stroke in primary care - a 9-year retrospective study

Jinghao Han1, Yue Kwan Choi1, Wing Kit Leung1

  • 1Department of Family Medicine, New Territories East Cluster, Hospital Authority, Hong Kong, China.

BMC Family Practice
|August 8, 2021
PubMed

Insights

Long-term outcomes for ischemic stroke patients in primary care are favorable. Statin use significantly reduces stroke recurrence and mortality, while lower diastolic blood pressure indicates higher risk.

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Primary Care Research

Background:

  • Investigating long-term prognosis of ischemic stroke patients within primary care settings.
  • Identifying risk factors for recurrent cardiovascular events and all-cause mortality post-stroke.

Purpose of the Study:

  • To document long-term outcomes in ischemic stroke patients.
  • To explore risk factors for recurrent cardiovascular events and all-cause mortality in primary care.

Main Methods:

  • Retrospective cohort study in Hong Kong general out-patient clinics.
  • Included ischemic stroke patients with regular follow-up from 2010 to 2018.
  • Used Cox proportional hazard models with competing risk adjustment for cause-specific hazard ratios.

Main Results:

  • 466 patients (mean age 71.5 years) followed for a median of 8.7 years.
  • 17.2% experienced recurrent stroke; 12.2% developed coronary artery disease (CAD).
  • Statin therapy significantly reduced recurrent stroke (csHR=0.476) and all-cause mortality (HR=0.693). Age was an independent risk factor for adverse outcomes. Female sex, antiplatelet use, and higher diastolic blood pressure predicted survival.

Conclusions:

  • Ischemic stroke patients in primary care have a favorable long-term prognosis.
  • Statin use is linked to decreased stroke recurrence and mortality.
  • Lower baseline diastolic blood pressure is associated with increased mortality, emphasizing its clinical importance.
Abstract

Keywords:
Cardiovascular disease (CVD) riskPrimary careSecondary preventionStatinStroke

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