Related Experiment Video
Updated: Oct 25, 2025

08:21
A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions
Published on: February 5, 2016
22.3K
Gold nanoclusters: An ultrasmall platform for multifaceted applications
Sonia1, Komal1, Shrikant Kukreti2
1Nano-bioconjugate Chemistry Lab, Cluster Innovation Centre, University of Delhi, Delhi, India; Nucleic Acids Research Laboratory, Department of Chemistry, University of Delhi, Delhi, India.
Talanta
|August 8, 2021
Summary
Gold nanoclusters (Au NCs) below 2 nm exhibit unique properties. This review covers their synthesis, properties, and applications in biosensing, bio-imaging, and catalysis.
Area of Science:
- Nanomaterials Science
- Chemistry
Background:
- Gold nanoclusters (Au NCs) are sub-2 nm nanomaterials with distinct properties compared to bulk gold.
- Their unique characteristics stem from quantum confinement and surface effects, enhanced by templating or ligand assistance for stability and high quantum yield.
Purpose of the Study:
- To review the solution phase synthesis and fundamental properties of Au NCs.
- To provide a comprehensive overview of recent advancements in Au NCs for biosensing, bio-imaging, enzyme mimicry, temperature sensing, and catalysis.
Main Methods:
- Literature review of synthesis strategies for Au NCs.
- Analysis of research on Au NCs in various application domains.
Main Results:
- Au NCs possess tunable and sensitive physicochemical properties.
- Recent studies demonstrate significant progress in Au NC-based biosensors, bio-imaging probes, enzyme mimics, temperature sensors, and catalysts.
Conclusions:
- Au NCs offer versatile platforms for advanced applications due to their unique properties.
- Further research into challenges and future prospects will drive the multifaceted applications of Au NCs.

