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Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
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New potential application of hydroxypropyl-β-cyclodextrin in solid self-nanoemulsifying drug delivery system and

Jung Suk Kim1, Yoo Jin Choi1, Mi Ran Woo1

  • 1College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.

Carbohydrate Polymers
|August 8, 2021
PubMed
Summary

Hydroxypropyl-β-cyclodextrin (HP-β-CD) enhances dexibuprofen solubility and oral bioavailability when used as a carrier in novel solid self-nanoemulsifying drug delivery systems (SNEDDS). This approach improves drug delivery for poorly water-soluble compounds.

Keywords:
DexibuprofenHydroxypropyl-β-cyclodextrinOral bioavailability enhancementSelf-nanoemulsifying drug delivery systemSolid hydrophilic carrier

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