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Updated: Oct 25, 2025
Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor
Published on: May 2, 2025
Carbamazepine-induced immune thrombocytopenia confirmed by modified MASPAT test
Weiyuan Chen1, Xiaoying Lv1, Ruiming Rong2
1Department of Transfusion, Zhongshan Hospital Xiamen Branch, Fudan University, Xiamen, 361015, China.
Abstract:
A 76-year-old man suffering post-herpetic neuralgia developed severe thrombocytopenia 15 days after the administration of carbamazepine. Carbamazepine-dependent platelet antibodies were proved to be present in the patient's serum by a modified Monoclonal Antibody Solid-phase Platelet Antibody Test (MASPAT), and the diagnosis of carbamazepine-induced immune thrombocytopenia was confirmed. For the patient, carbamazepine should be advised to be avoided permanently. The present report advocated the application of a modified MASPAT test for the detection of carbamazepine-dependent platelet antibodies.
