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Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
Published on: March 17, 2022
A Multi-Site Thailand Heart Failure Snapshot Study.
Thitipong Tankumpuan1, Siriorn Sindhu1, Nancy Perrin2
1Mahidol University, Faculty of Nursing, Bangkok, Thailand.
Heart failure (HF) patients in Thai university hospitals showed greater frailty and depressive symptoms, despite advanced care. This highlights the need for tailored interventions considering social determinants for better HF management in Thailand.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- Increasing heart failure (HF) prevalence in low- and middle-income countries necessitates better data for health service planning.
- Limited community-level data on HF patient profiles and outcomes hinders effective healthcare strategies.
- Thailand faces challenges in managing rising HF rates due to data gaps.
Purpose of the Study:
- To document demographic, clinical, and sociodemographic characteristics of heart failure patients in Thailand.
- To compare clinical outcomes of heart failure patients based on hospital level.
- To inform health service planning and interventions for heart failure management.
Main Methods:
- Multi-site, observational study (Thai HF Snapshot Study) conducted from June 2017 to June 2019.
- Recruitment of 512 participants across various hospital levels in Thailand.
- Data collection on patient characteristics and clinical outcomes.
Main Results:
- The study included 512 participants (55.9% female, mean age 64.9 years).
- Ischaemic heart disease was the most common admitting diagnosis (45.1%).
- Patients in university hospitals exhibited higher frailty (p=0.015), more depressive symptoms (p<0.001), and lower functional status (p<0.001) compared to tertiary care.
Conclusions:
- Despite access to advanced technology and specialists, heart failure patients in Thai university hospitals presented with greater acuity.
- Clinical outcomes suggest a need for improved heart failure management strategies.
- Interventions must address social determinants of health to enhance HF care in Thailand.
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