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Updated: Oct 25, 2025

Multifractal Spectrum Analysis for Assessing Pulmonary Nodule Malignancy
Published on: January 10, 2025
Comparative analysis of pulmonary nodules segmentation using multiscale residual U-Net and fuzzy C-means clustering
Jianshe Shi1, Yuguang Ye2, Daxin Zhu2
1Fujian Provincial Key Laboratory of Data Intensive Computing, Quanzhou Normal University, Quanzhou 362000, China; Department of General Surgery, Huaqiao University Affiliated Strait Hospital, Quanzhou, Fujian 362000, China; Key Laboratory of Intelligent Computing and Information Processing, Quanzhou Normal University, Fujian Province University, Quanzhou 362000, China.
Background And Objective:
Pulmonary nodules have different shapes and uneven density, and some nodules adhere to blood vessels, pleura and other anatomical structures, which increase the difficulty of nodule segmentation. The purpose of this paper is to use multiscale residual U-Net to accurately segment lung nodules with complex geometric shapes, while comparing it with fuzzy C-means clustering and manual segmentation.
Method:
We selected 58 computed tomography (CT) scan images of patients with different lung nodules for image segmentation. This paper proposes an automatic segmentation algorithm for lung nodules based on multiscale residual U-Net. In order to verify the accuracy of the method, we also conducted comparative experiments, while comparing it with fuzzy C-means clustering.
Results:
Compared with the other two methods, the segmentation of lung nodules based on multiscale residual U-Net has a higher accuracy, with an accuracy rate of 94.57%. This method not only maintains a high accuracy rate, but also shortens the recognition time significantly with a segmentation time of 3.15 s.
Conclusions:
The diagnosis method of lung nodules combined with deep learning has a good market prospect and can improve the efficiency of doctors in diagnosing benign and malignant lung nodules.

