BIOELECTRICAL IMPENDANCE ANALYSIS OF BODY COMPOSITION IN PATIENTS WITH CHRONIC HEART FAILURE
N Gulatava1, N Tabagari1, S Tabagari1
1David Tvildiani Medical University, Tbilisi, Georgia.
Insights
Body composition analysis in chronic heart failure patients reveals differences in fat-free mass and reactance compared to healthy individuals. Female patients showed significant variations in resistance and lean body mass.
Area of Science:
- Clinical Medicine
- Cardiology
- Body Composition Analysis
Background:
- Body composition is crucial for understanding health outcomes in diverse populations, particularly in chronic heart failure (CHF).
- Body fat mass and fat-free mass significantly influence CHF severity, patient outcomes, and quality of life.
Purpose of the Study:
- To analyze body composition parameters in patients diagnosed with chronic heart failure.
- To compare body composition metrics between CHF patients and a control group of healthy individuals.
Main Methods:
- Included 86 CHF patients and 30 healthy controls.
- Evaluated body mass, height, waist/hip circumference, and anthropometric measurements.
- Utilized Bioelectrical Impedance Analysis (BIA) for fat-free mass (FFM) determination and other parameters.
Main Results:
- Both groups exhibited underweight, overweight, and obesity (by BMI).
- Significant differences observed between CHF patients and controls in Reactance and FFM (kg) (P<0.009).
- Female CHF patients showed significant differences in resistance, lean body mass, and FFM (kg) compared to controls.
Conclusions:
- Body composition analysis is valuable for CHF patients.
- CHF functional classes correlate with variations in BIA-derived parameters like resistance and lean body mass.
- Specific BIA parameters differ between male and female CHF patients and healthy individuals.
Abstract:
Evaluation of body composition is important in countries of different populations and morbidities. One of the groups of morbidity consists of patients with chronic heart failure, where the body fat mass as well as fat-free mass and several other parameters are likely to have an impact on severity and/or outcome of the disease and patient's quality of life. The purpose of the study was to analyze the parameters of body composition in patients with chronic heart failure. Study included 86 patients, fit for the purpose of the study, and 30 practically healthy individuals. Body mass and other measurement data (height, waist circumference, hip circumference and waist-to-hip ratio, anthropometric measurements) were evaluated. Bioelectrical impedance (BIA) was analyzed by BIA 450, BIODYNAMICS (USA) in accordance with standard procedures that are widely accepted. Fat free mass (FFM) was determined by the BIA method. This index was also calculated by prediction equation based on BIA and anthropometric parameters: FFM (kg) = 11.78 + (0.499 x H2/R) + (0.134 x Weight) + (3.449 x gender), where H stands for height in cm, R represents resistance in Ω, Weight is measured in kg and "gender" equals to 0 for females and 1 - for males (3). FFMI equals to the ratio of FFM (kg) to the square of the height; Ratio of FMI - FM (kg) to the square of the height. Study showed that in both patients' and control groups, underweight, as well as overweight individuals are present; also, in both groups, obesity, as BMI category, is most common. Groups (patients vs control) differed in Reactance and FFM (kg) (P<0.009). There was no statistically significant difference between male subgroups of patient and control groups; Valid differences in resistance, lean body mass and fat free mass (kg) were observed between female subgroups. Analysis of body composition characteristics in patients with chronic heart failure revealed that functional classes of heart failure differ in several BIA data, including resistance, Lean body mass (kg) and Fat Free Mass (%).
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