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Updated: Oct 25, 2025

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
Published on: January 3, 2025
Next-Generation Breeding Strategies for Climate-Ready Crops
Ali Razzaq1, Parwinder Kaur2, Naheed Akhter3
1Centre of Agricultural Biochemistry and Biotechnology (CABB), University of Agriculture, Faisalabad, Pakistan.
Next-generation breeding tools, including genomic-assisted breeding and CRISPR/Cas systems, are crucial for developing climate-resilient crops. These innovations enhance crop productivity to ensure global food security for a growing population.
Area of Science:
- Agricultural Science
- Genetics
- Biotechnology
Background:
- Climate change significantly threatens global food security by reducing crop productivity.
- The projected increase in global population to over 10 billion necessitates enhanced food production strategies.
Purpose of the Study:
- To review next-generation breeding tools for developing climate-resilient crops.
- To explore strategies for improving crop production to meet future food demands.
Main Methods:
- Genomic-assisted breeding (GAB) utilizing crop pan-genomes to capture genetic diversity.
- Genome editing technologies, including CRISPR/Cas systems (prime editing, base editing) and versatile Cas orthologs.
- High-throughput phenotyping, artificial intelligence (AI), machine learning (ML), and speed breeding.
Main Results:
- Pan-genomes offer new avenues to exploit genetic variation for crop optimization.
- CRISPR/Cas systems demonstrate broad applications in crop research for stress resistance.
- Integration of advanced tools accelerates crop improvement and gene discovery.
Conclusions:
- Next-generation breeding platforms are essential for developing climate-ready crops.
- Innovations in breeding, microbiome applications, and underutilized crops are key to future food security.
- Digitalization and automation in agriculture, driven by AI and ML, will further enhance crop improvement efforts.
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