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A REDCap-based model for online interventional research: Parent sleep education in autism
Beth A Malow1, Anjalee Galion2, Frances Lu3
1Sleep Disorders Division, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Journal of Clinical and Translational Science
|August 9, 2021
Summary
Online platforms efficiently delivered a sleep intervention to parents of children with autism spectrum disorder (ASD), improving some sleep measures. This demonstrates feasibility for pediatric research.
Area of Science:
- Pediatric Healthcare Research
- Autism Spectrum Disorder (ASD) Research
- Clinical and Translational Science
Background:
- Online platforms offer timely solutions for pediatric healthcare research, especially during pandemics.
- These platforms streamline trial processes like electronic consent, randomization, data collection, intervention delivery, and analysis.
- The study focused on delivering a sleep disorder intervention to parents of children with ASD.
Purpose of the Study:
- To assess the feasibility of an online digital platform for delivering a sleep intervention to parents of children with ASD.
- To evaluate the effectiveness of multimedia materials compared to a pamphlet alone in improving sleep habits.
- To explore the impact of the intervention on parental sense of competence.
Main Methods:
- A multicenter study utilized an online platform to deliver sleep disorder intervention to parents of children with ASD.
- Participants were randomized to receive either a sleep education pamphlet or the pamphlet plus multimedia materials (quick-tips sheets and videos).
- Validated measures (FISH, CSHQ-ASD, PSOC) were completed pre- and post-intervention (12 weeks).
Main Results:
- Enrollment exceeded recruitment goals, with improved trial efficiency in data entry and participant notifications.
- No significant improvements were observed in primary study measures for either the pamphlet or multimedia groups.
- However, parents reporting improved sleep habits (FISH score ≥3) showed a significant improvement in the CSHQ-ASD total score (P=0.038).
Conclusions:
- Online research delivery platforms are feasible for studies involving children with ASD and broader pediatric clinical research.
- These platforms enhance participant inclusion, convenience, and safety for both participants and research personnel.
- The findings support the use of digital tools to improve the efficiency and accessibility of pediatric research.
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