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Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture
Published on: July 10, 2013
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On the progress of 3D-printed hydrogels for tissue engineering.
Rigoberto C Advincula1,2,3, John Ryan C Dizon4, Eugene B Caldona1
1Department of Chemical and Biomolecular Engineering and Joint Institute for Advanced Materials, University of Tennessee, Knoxville, TN 37996 USA.
MRS Communications
|August 9, 2021
Summary
3D bioprinting utilizes hydrogels and cells to create living tissues. This study reviews hydrogel materials, design, and future applications in biomedical engineering.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Additive Manufacturing
Background:
- Additive manufacturing (3D printing) is revolutionizing fields like medicine and aerospace.
- 3D bioprinting enables the creation of scaffolds and functional living tissues using biomaterials and cells.
Purpose of the Study:
- To classify and explore applications of hydrogels in 3D printing.
- To discuss design considerations, including physical and biological parameters, for producing 3D printed hydrogels.
- To outline future perspectives in 3D printing hydrogels for biomedical and bioengineering.
Main Methods:
- Review of current literature on hydrogel materials for 3D printing.
- Classification of hydrogels based on their properties and applications.
- Analysis of design parameters for successful 3D printing of hydrogels.
Main Results:
- Hydrogels are classified, and their diverse applications in 3D printing are presented.
- Key materials for 3D printing hydrogels include biopolymers, synthetic polymers, and nanocomposites.
- Design considerations encompass physical properties (e.g., viscosity, crosslinking) and biological parameters (e.g., cell viability).
Conclusions:
- 3D printing of hydrogels is crucial for advancing tissue engineering and regenerative medicine.
- Future directions include novel materials, 4D printing, and innovative printing technologies.
- Continued research promises enhanced biomedical and bioengineering applications through advanced hydrogel-based 3D printing.
