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Updated: Oct 25, 2025

Diffuse Reflectance Spectroscopy: Getting the Capillary Refill Test Under One's Thumb
Published on: December 2, 2017
Point-Of-Care Capillary Refill Technology Improves Accuracy of Peripheral Perfusion Assessment.
David C Sheridan1,2, Robert L Cloutier1, Ravi Samatham3
1Department of Emergency Medicine, Oregon Health & Science University, Portland, OR, United States.
A new non-invasive sensor improves capillary refill time (CRT) assessment, offering a more precise and repeatable method for evaluating peripheral perfusion compared to subjective clinical judgment.
Area of Science:
- Critical Care Medicine
- Biomedical Engineering
- Physiology
Background:
- Capillary refill time (CRT) is a standard bedside method for assessing peripheral perfusion.
- CRT aids in recognizing conditions like sepsis and guiding therapeutic interventions.
- Current manual CRT assessment by clinicians exhibits significant variability.
Purpose of the Study:
- To evaluate a novel non-invasive finger sensor for objective CRT measurement.
- To compare device-based CRT assessment with expert assessment and clinical provider assessment.
- To determine if new technology can enhance the precision and repeatability of CRT measurements.
Main Methods:
- Prospective, observational study conducted in intensive care and emergency departments.
- Utilized a non-invasive finger sensor to measure CRT.
- Compared device CRT measurements against trained research personnel (gold standard) and clinical providers.
Main Results:
- Device CRT showed a strong correlation (Pearson r=0.693) with research personnel CRT.
- Clinical provider CRT demonstrated a weaker correlation (Pearson r=0.359) with research personnel CRT.
- 89 pairs of measurements were analyzed.
Conclusions:
- Point-of-care technology offers a promising solution for improving peripheral perfusion assessment.
- Standardized CRT measurement via technology can enhance the translation of critical care research.
- Objective CRT assessment is crucial for emergency department triage and resuscitation efforts.
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