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Updated: Oct 25, 2025

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
Yewlin E Chee1, Raghu Mudumbai1, Steven S Saraf1
1Department of Ophthalmology, University of Washington, Seattle, WA, USA.
Purpose:
To describe two cases of medium-sized uveal melanoma presenting with hemorrhagic choroidal detachments.
Observations:
The first case is a 39-year-old man who presented with choroidal hemorrhage and angle closure glaucoma. The second case is a 42-year-old man who presented with choroidal hemorrhage and posterior scleritis. Vitrectomy with transvitreous fine needle aspiration biopsy was ultimately required to diagnose malignant uveal melanoma in each case.
Conclusions And Importance:
Intraocular hemorrhage is a rare presenting sign of uveal melanoma. When it does occur, it is typically associated with large tumors. Hemorrhagic choroidal detachments are particularly rare in uveal melanoma, and can limit the diagnostic utility of clinical exam, B-scan ultrasonography, and magnetic resonance imaging. Although it is uncommon, it is important to maintain a high index of suspicion for choroidal melanoma in any patient with unexplained choroidal hemorrhage.
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