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Published on: February 12, 2018
Stromal microsporidial keratitis successfully treated with medical therapy
Christopher P Donovan1, Curtis E Margo1,2, Edgar M Espana1,3
1Department of Ophthalmology, University of South Florida, Morsani College of Medicine, 13330 USF Laurel Drive, 4th Floor, Tampa, FL, 33612, USA.
Purpose:
To report a case of severe stromal microsporidal keratitis successfully treated with oral albendazole and topical voriconazole.
Observations:
A 71-year-old man presented with progressive vision loss and corneal opacification for one year. Initial visual acuity was counting fingers attributed to a dense subepithelial opacification. Confocal microscopy and subsequent corneal biopsy lead to the diagnosis of microsporidial keratitis. The patient completed a four-week course of oral albendazole and topical voriconazole which resulted in resolution of the corneal opacification and improvement in visual acuity to 20/250.
Conclusions And Importance:
A four-week course of oral albendazole and topical voriconazole was an effective treatment for severe stromal microsporidial keratitis.
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