Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

94
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
94
Allergic Reactions02:06

Allergic Reactions

29.4K
Overview
29.4K
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.1K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.1K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

3.4K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
3.4K
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

57
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
57
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

863
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
863

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simulation-based training in cardiovascular intervention and cardiac surgery: bridging skill, safety, and innovation.

European heart journal·2026
Same author

Comparative Efficacy of Continuous Versus Patch ECG Monitoring in Detecting Atrial Fibrillation Recurrence Post Catheter Ablation: Insights From the REAL-AF Registry.

Journal of cardiovascular electrophysiology·2026
Same author

Predictors of Procedural and Clinical Outcomes Following Transcatheter Tricuspid Edge-to-Edge Repair: An Expert Overview.

JACC. Cardiovascular interventions·2026
Same author

Advanced Imaging in Loeffler Endocarditis in the Setting of Dupilumab-Associated Hypereosinophilia: Diagnostic Utility of Cardiac MRI.

Circulation. Cardiovascular imaging·2026
Same author

Feature Mapping of Native Oxygenation-Sensitive CMR Images for Classifying Cardiomyopathies.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance·2026
Same author

Cardiac magnetic resonance predictors of adverse outcomes in Chagas cardiomyopathy.

Frontiers in cardiovascular medicine·2026

Related Experiment Video

Updated: Oct 25, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
03:23

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

1.0K

Eosinophilic Myocarditis: When Allergies Attack the Heart!

Vardhmaan Jain1, Agam Bansal1, Devika Aggarwal2

  • 1From the Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH.

Cardiology in Review
|August 9, 2021
PubMed
Summary
This summary is machine-generated.

Eosinophilic myocarditis involves heart muscle injury from eosinophils. Diagnosis uses imaging and biopsy, with treatment targeting the eosinophilia cause for better outcomes.

More Related Videos

Humanized Mediator Release Assay as a Read-Out for Allergen Potency
10:22

Humanized Mediator Release Assay as a Read-Out for Allergen Potency

Published on: June 29, 2021

3.7K
Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells
12:46

Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells

Published on: August 17, 2022

2.8K

Related Experiment Videos

Last Updated: Oct 25, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
03:23

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

1.0K
Humanized Mediator Release Assay as a Read-Out for Allergen Potency
10:22

Humanized Mediator Release Assay as a Read-Out for Allergen Potency

Published on: June 29, 2021

3.7K
Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells
12:46

Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells

Published on: August 17, 2022

2.8K

Area of Science:

  • Cardiology
  • Immunology
  • Pathology

Background:

  • Eosinophilic myocarditis is myocardial injury driven by eosinophilic infiltration.
  • Underlying causes include hypereosinophilic syndromes (reactive, clonal, idiopathic).
  • Presentations range from subclinical to fulminant, with potential for thromboembolic events and fibrosis.

Purpose of the Study:

  • To summarize the clinical presentation, diagnosis, and management of eosinophilic myocarditis.
  • To highlight the diverse etiologies of eosinophilia leading to cardiac involvement.
  • To outline diagnostic strategies and therapeutic approaches.

Main Methods:

  • Review of clinical presentations and diagnostic findings.
  • Emphasis on multimodality imaging and endomyocardial biopsy for diagnosis.
  • Discussion of treatment strategies based on underlying causes.

Main Results:

  • Eosinophilic myocarditis can manifest with varied severity and complications like fibrosis.
  • Diagnosis requires comprehensive evaluation including imaging and biopsy.
  • Successful management hinges on identifying and treating the root cause of eosinophilia.

Conclusions:

  • Eosinophilic myocarditis is a serious condition requiring prompt diagnosis and tailored treatment.
  • Addressing the underlying cause of eosinophilia is crucial for patient outcomes.
  • Multimodality imaging and biopsy are key diagnostic tools.