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Effectiveness of Concentrated Growth Factor on Surgical Wound Healing: A Pilot Study
R S Kabilamurthi1, Rajendra Prabhu Abhinav2, Nesappan Thiyaneswaran3
1Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science Saveetha University, Chennai 77, India.
Aim:
The aim of the current study is to assess and evaluate the effectiveness of concentrated growth factors on wound healing after implant placement procedures.
Methodology:
Twenty-four patients who underwent implant placement were included in the study and were divided into two groups (group 1 = non-CGF group; group 2 = CGF group). Conventional implant placement was done in both the groups followed by placement of CGF membrane and closure using 3-0 silk in the CGF group and only closure using 3-0 silk sutures in the control group. The patients were asked to report on the 3rd and 7th day respectively and the wound healing was assessed using an early wound healing index given by Lorenzo Marini.
Statistical Analysis:
Shapiro-Wilk test was used to test the normality of the test, which was found to deviate from normal distribution and hence Mann-Whitney U test was employed to evaluate the statistical significance of the two independent samples.
Results:
The mean ± SD was found to be 6.17 ± 2.04 for the control (group 1) and 5.67 ± 0.51 for CGF group (group 2) on the 3rd day. The mean and SD of control group and test group on the 7th day was 7 ± 1.55 and 9.33 ± 1.63, respectively. The difference between the groups on the 7th day was found to be statistically significant (P value < 0.05).
Conclusion:
Concentrated growth factor application had positive effects on surgical wound healing after implant placement.
