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Related Concept Videos

Gene Therapy00:59

Gene Therapy

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
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Overview
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Animal Mitochondrial Genetics02:59

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Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
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Microorganisms in Medicine and Therapeutics01:29

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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Updated: Oct 25, 2025

Author Spotlight: Addressing Regulatory Gaps in Molecular Studies by Quantifying Viral Vectors in Complex Matrices
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Human gene therapy: A patent analysis.

Wuyuan Zhou1, Xiang Wang2

  • 1Zhejiang Academy of Science and Technology Information, Hangzhou 310006, China.

Gene
|August 9, 2021
PubMed
Summary
This summary is machine-generated.

Gene therapy patent analysis reveals the US leads globally, but China is rapidly advancing. Key technologies include gene biology, disease treatment, delivery methods, and viral vectors like Adeno-Associated Virus.

Keywords:
Gene therapyInventionsPatent analysisTechnological competitiveness

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Area of Science:

  • Biotechnology
  • Intellectual Property Law
  • Genetics

Background:

  • Gene therapy, despite its revolutionary potential, faces challenges from clinical trial failures and ethical concerns.
  • A lack of comprehensive analysis of global gene therapy patents hinders understanding of the field's development.

Purpose of the Study:

  • To propose a robust method for retrieving gene therapy patents.
  • To analyze the global patent landscape of gene therapy to identify trends and key players.

Main Methods:

  • Development and application of a novel patent retrieval methodology.
  • Systematic analysis of global gene therapy patent data.

Main Results:

  • The United States dominates the gene therapy patent landscape, with China emerging as a significant recent leader.
  • Chinese institutions are increasingly surpassing US entities in patent filings.
  • Key technology areas include gene biology, disease targets, delivery methods (Adeno-Associated Virus, Retrovirus, Lentivirus post-2014), and adverse event management.

Conclusions:

  • The study provides a clear picture of the global gene therapy patent landscape, highlighting shifting leadership dynamics.
  • Findings offer evidence-based insights for scientific research management and strategic decision-making in gene therapy development.