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Updated: Oct 25, 2025
Author Spotlight: Optimizing Growth Factors for Production of Biotechnologically Relevant Secondary Metabolites
Published on: October 25, 2024
"Light modulates transcriptomic dynamics upregulating astaxanthin accumulation in Haematococcus: A review"
Ankesh Ahirwar1, Gurvan Meignen1, Mohd Jahir Khan2
1Diatom Nanoengineering and Metabolism Laboratory (DNM), School of Applied science, Dr. Harisingh Gour Central University, Sagar, MP 470003, India; Metabolism, Engineering of Microalgal Molecules and Applications (MIMMA), Mer Molecules Santé, Molecules & Health (EA 2160), Le Mans University, IUML - FR 3473 CNRS, Le Mans, France.
Abstract:
Haematococcus pluvialis is a green alga that can accumulate high astaxanthin content, a commercially demanding market keto food. Due to its high predicted market value of about 3.4 billion USD in 2027, it is essential to increase its production. Therefore, it is crucial to understand the genetic mechanism and gene expressions profile during astaxanthin synthesis. The effect of poly- and mono-chromatic light of different wavelengths and different intensities have shown to influence the gene expression towards astaxanthin production. This includes transcriptomic gene analysis in H. pluvialis underneath different levels of illumination stress. This review has placed the most recent data on the effects of light on bioastaxanthin production in the context of previous studies, which were more focused on the biochemical and physiological sides. Doing so, it contributes to delineate new ways along the biotechnological process with the aim to increase bioastaxanthin production while decreasing production costs.
