Long COVID in Children: Observations From a Designated Pediatric Clinic

Liat Ashkenazi-Hoffnung1,2, Einat Shmueli1,2, Shay Ehrlich1,2

  • 1From the Day Care Hospitalization, Pulmonary Institute and Heart Institute, Schneider Children's Medical Center of Israel.

Insights

Pediatric long COVID often causes functional impairment in children, with nearly 60% experiencing symptoms 1-7 months post-infection. Many show mild respiratory abnormalities, highlighting the need for further research into long COVID in children.

Area of Science:

  • Pediatric Medicine
  • Infectious Diseases
  • Public Health

Background:

  • Systematic data on pediatric long COVID are limited.
  • Persistent symptoms post-COVID-19 infection in children require thorough investigation.
  • Multidisciplinary clinics are emerging to manage complex pediatric conditions.

Purpose of the Study:

  • To prospectively assess children with persistent symptoms following COVID-19 infection.
  • To characterize the functional impairment and clinical findings in pediatric long COVID.
  • To evaluate the utility of multidisciplinary clinics in managing pediatric long COVID.

Main Methods:

  • Prospective assessment of 90 children with persistent symptoms.
  • Evaluation at a designated multidisciplinary long COVID clinic.
  • Comprehensive structured clinical and functional assessment.

Main Results:

  • Nearly 60% of children experienced functional impairment 1-7 months after infection onset.
  • Mild abnormal findings were observed in approximately half of the patients.
  • Respiratory system abnormalities were the most frequent finding.

Conclusions:

  • Pediatric long COVID can lead to significant functional impairment.
  • A substantial proportion of children exhibit persistent symptoms and mild abnormalities.
  • Early and comprehensive assessment in specialized clinics is crucial for managing pediatric long COVID.

Related Concept Videos

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
2.7K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
765
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
47
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
57
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
218
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.0K