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Updated: Oct 25, 2025

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Published on: April 26, 2024
Association between poor sleep for infants to two years and subsequent mental health symptoms: A systematic review
Beth L Mah1,2, Kate Larkings2,3
1224531Karitane Mothercraft Society, Sydney, Australia.
Insights
Poor infant sleep, or sleep problems in babies up to age two, is linked to a higher risk of developing mental health symptoms later in life. Early identification and intervention are crucial for at-risk infants.
Area of Science:
- Developmental Psychology
- Pediatric Sleep Medicine
- Mental Health Research
Background:
- Sleep is intricately linked to mental health across the lifespan.
- The predictive value of early childhood sleep disturbances for later mental health outcomes remains unclear.
- Infant sleep quality significantly impacts infant and family well-being.
Purpose of the Study:
- To systematically review and meta-analyze the association between poor infant sleep (up to age two) and subsequent mental health symptoms.
- To quantify the risk of developing mental health issues linked to early sleep problems.
Main Methods:
- Systematic literature search across major databases (Medline, Embase, CINAHL, PsycINFO, Web of Science, Cochrane).
- Adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
- Inclusion of 17 relevant studies for meta-analysis.
Main Results:
- A combined adjusted odds ratio of 1.65 (95% CI = 1.34, 2.05) indicated a significant association between infant sleep problems and later mental health symptoms.
- Heterogeneity in outcome measures for both sleep and mental health was noted, potentially limiting generalizability.
Conclusions:
- Poor infant sleep is a significant risk factor for the development of future mental health disorders.
- Early identification of sleep disturbances in infancy is vital for timely intervention strategies.
- Further research with standardized measures is needed to strengthen generalizability.
Abstract:
Sleep plays a complex bidirectional role in the life span of most mental health illness. How soon poor sleep becomes an indicator of future mental illness is unknown. Infant sleep is a complex concept which can impact greatly on both baby and family well-being. Thus, a systematic review and meta-analysis were conducted to investigate whether poor infant sleep to age two is associated with future mental health symptoms. A systematic search of Medline, Embase, CINAHL, PsycINFO, Web of Science and Cochrane was conducted, using PRISMA guidelines. The search resulted in 17 articles to include in this review. A combined adjusted odds ratios of 1.65 (95% CI = 1.34, 2.05) for infant sleep problems leading to subsequent mental health symptoms resulted. A variety of outcome measures for both poor infant sleep and mental health symptoms/diagnosis were used, limiting the generalisability of results. Poor sleep in infancy should be considered one of many risk factors for future mental health disorder signifying the importance of early intervention.
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