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An Aggressive growth of cranial sarcoma
Ramani Thiagarajah1, Pulivendhan Sellamuthu1, Sarwinder Singh Bharmjit Singh1
1Department of Neurosurgery, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia.
BMJ Case Reports
|August 10, 2021
Summary
This case report details a rare, large cranial sarcoma, a malignant connective tissue tumor. Surgical removal and reconstruction were successful, with no residual tumor found post-operation.
Area of Science:
- Oncology
- Surgical Pathology
- Neurosurgery
Background:
- Sarcomas are rare malignant tumors originating from connective tissues.
- Head and neck sarcomas account for less than 1% of all sarcoma occurrences.
- Cranial sarcomas are exceptionally rare, posing unique diagnostic and surgical challenges.
Observation:
- A case of an exceptionally large cranial sarcoma is presented.
- The tumor weighed approximately 1.1 kg.
- Surgical management involved gross total excision, pedicle skin grafting, and titanium mesh cranioplasty.
Findings:
- Histopathological examination revealed primitive intermediate-sized tumor cells.
- Tumor cells were arranged in sheets, nests, and cords with focal palisading.
- Postoperative MRI confirmed no evidence of residual tumor two weeks after surgery.
Implications:
- This case highlights the possibility of massive cranial sarcomas, despite their rarity.
- Successful surgical resection and reconstruction are feasible for large cranial tumors.
- Complete tumor excision is critical for favorable patient outcomes in cranial sarcoma cases.

