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Updated: Oct 25, 2025

Translational Orthotopic Models of Glioblastoma Multiforme
Published on: February 17, 2023
An Aggressive growth of cranial sarcoma
Ramani Thiagarajah1, Pulivendhan Sellamuthu1, Sarwinder Singh Bharmjit Singh1
1Department of Neurosurgery, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia.
Abstract:
Sarcomas are a group of rare malignant tumours of the connective tissues. They can occur in almost any location, but more frequently in the extremities. The occurrence of sarcomas in the head and neck region is less than 1%. We are presenting a case report of a very large cranial sarcoma. Gross total tumour excision was done with pedicle skin graft and titanium mesh cranioplasty. The excised tumour weighed approximately 1.1 kg. Histopathological examination showed primitive intermediate-sized tumour cells arranged in sheets, nests and cords with focal palisading. Postoperative MRI done 2 weeks post surgery showed no evidence of residual tumour.

