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Acetic acid bioproduction: The technological innovation change.
Giulia Merli1, Alessandro Becci1, Alessia Amato1
1Department of Life and Environmental Sciences, Università Politecnica delle Marche, 60131 Ancona, Italy.
Sustainable acetic acid production is gaining interest. Patent analysis reveals a shift towards genetic engineering and agricultural waste for acetic acid bacteria, while acetogenic bacteria focus on synthesis gas for greener processes.
Area of Science:
- Biotechnology
- Industrial Microbiology
- Chemical Engineering
Background:
- Acetic acid is a globally important organic acid with increasing demand.
- Sustainable production methods are crucial due to growing industrial needs.
- Biological routes, including acetogenesis and aerobic fermentation, offer sustainable alternatives.
Purpose of the Study:
- To analyze technological innovation in acetic acid bioproduction through international patent data.
- To provide a worldwide overview of inventions from 1990 to 2020.
- To identify trends in sustainable acetic acid production processes.
Main Methods:
- International patent analysis using the Espacenet platform (1990-2020).
- Review of representative literature on operating conditions (temperature, pH, oxygenation).
- Focus on technological innovation and state-of-the-art advancements.
Main Results:
- Consistent patent activity for acetic acid bacteria, with recent focus on genetic engineering (36%) and agricultural waste (26%).
- Acetogenic bacteria production is a recent development, with over 90% of patents in the last decade.
- Acetogenic bacteria patents primarily explore synthesis gas as a sustainable substrate.
Conclusions:
- Ongoing interest in acetic acid bioproduction by both acetogenic and acetic acid bacteria.
- Acetic acid bacteria production is evolving towards circular economy principles.
- Acetogenic bacteria offer a promising route for sustainable acetic acid production using synthesis gas.
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