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Related Concept Videos

Catenins01:23

Catenins

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Catenins are characterized by multiple binding domains and dynamic structures that allow them to function as linker proteins in cell junction complexes. All catenins, except α-catenin, contain a characteristic protein sequence called the armadillo repeat and are therefore also called armadillo proteins.
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Fibrous Proteins00:55

Fibrous Proteins

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Fibrous proteins are either long and narrow proteins or assemble to form long and thin structures. They contain repetitive units and usually consist of either alpha helices or beta sheets and, in rare cases, a mix of both. The amino acids in the primary structure often consist of repeating amino acid sequences. The role of fibrous proteins is primarily structural. Many are located in the extracellular matrix and are present in connective tissues to impart strength and joint mobility. They are...
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Tension Response at Adherens Junctions01:26

Tension Response at Adherens Junctions

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The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
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Tight Junctions01:29

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Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in multicellular organisms. They are mainly composed of claudin and occludin transmembrane proteins, and other proteins such as tricellulin and JAM (junctional adhesion molecule). All these proteins are 4-pass transmembrane proteins, except JAM, which is a single-pass transmembrane protein belonging to the immunoglobulin superfamily. The...
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The Sarcomere01:08

The Sarcomere

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A sarcomere is a microscopic segment repeating in a myofibril. The sarcomere fundamentally consists of two main myofilaments: thick filaments called myosin and thin filaments called actin. These filaments interact by sliding past each other in response to stimulus. In addition to myosin and actin, several other proteins, such as tropomyosin, troponin, titin, nebulin, myomesin, α-actinin, and dystrophin, play crucial roles in regulating, structuring, and functioning of the sarcomere.
Each...
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Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

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Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
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Related Experiment Video

Updated: Oct 25, 2025

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
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Teneurins.

Daniel T Pederick1, Liqun Luo1

  • 1Howard Hughes Medical Institute and Department of Biology, Stanford University, Stanford, CA 94305, USA.

Current Biology : CB
|August 10, 2021
PubMed
Summary

Daniel Pederick and Liqun Luo introduce teneurins, which are evolutionarily conserved type II transmembrane proteins. These proteins play crucial roles within the nervous system.

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Genetics

Background:

  • Teneurins are a family of evolutionarily conserved type II transmembrane proteins.
  • These proteins are known to play roles in the nervous system.

Purpose of the Study:

  • To introduce teneurins and their fundamental characteristics.
  • To highlight the significance of teneurins in neural functions.

Main Methods:

  • Literature review and synthesis of existing research on teneurins.
  • Analysis of protein structure and evolutionary conservation.

Main Results:

  • Teneurins are type II transmembrane proteins.
  • They are conserved across various species.

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  • They exhibit significant functions within the nervous system.

    • Conclusions:

    • Teneurins represent an important class of proteins for neural development and function.
    • Further research into teneurins is warranted to fully elucidate their mechanisms.