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Related Experiment Video

Updated: Oct 25, 2025

Studying Left Ventricular Reverse Remodeling by Aortic Debanding in Rodents

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Exercise Training Induces Left- but not Right-sided Cardiac Remodelling in Olympic Rowers.

Geert Kleinnibbelink^1,2,3, Nicole Panhuyzen-Goedkoop^4,5, Hugo Hulshof²

¹Department of Physiology, Research Insitute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

International Journal of Sports Medicine

|August 10, 2021

Summary

Increased training volume in elite rowers for 9 months led to left-sided cardiac remodeling, including increased left ventricular twist, with greater changes observed in female athletes. Right-sided cardiac structures remained unchanged.

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Area of Science:

Cardiology
Sports Medicine
Physiology

Background:

The athlete's heart is well-documented, but adaptations to increased training volume remain less understood.
Limited research exists on side-specific cardiac remodeling in response to intensified training.

Purpose of the Study:

To investigate the effects of a 9-month increase in training volume on cardiac structure, function, and mechanics in elite rowers.
To explore potential differences in cardiac remodeling between male and female athletes.

Main Methods:

Twenty-seven elite rowers underwent echocardiography before and after a 9-month period of increased weekly training hours.
Evaluated left- and right-sided cardiac structure, function, and mechanics, including strain and twist.

Main Results:

Increased training volume significantly enhanced left ventricular structure (wall thickness, diameter, volume, mass) and left ventricular twist.
Female rowers showed greater increases in left ventricular diameter and mass compared to male rowers.
No significant changes were observed in right ventricular or atrial structure, function, or mechanics.

Conclusions:

A 9-month increase in training volume induces left-sided cardiac structural remodeling and increased left ventricular twist in elite rowers.
Right-sided cardiac adaptations were not observed.
Sex-specific differences in left ventricular remodeling were noted, with females exhibiting larger adaptations.