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Analysis of Ear, Nose and Throat Manifestations in COVID-19 Patients
Mohammad Waheed El-Anwar1, Mohamed Eesa1, Waleed Mansour2
1Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Insights
Ear, nose, and throat symptoms are common in COVID-19 patients, including sore throat and nasal congestion. These ENT manifestations should be considered in COVID-19 diagnosis, especially when other symptoms are absent.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Respiratory Medicine
Background:
- Coronavirus disease 2019 (COVID-19) is a global pandemic primarily causing lower respiratory symptoms.
- However, upper respiratory tract symptoms, including ear, nose, and throat (ENT) manifestations, are also observed in COVID-19 patients.
Purpose of the Study:
- To investigate the prevalence of ENT manifestations in COVID-19 patients.
- To analyze the relationship between ENT symptoms and other COVID-19 manifestations and disease severity.
Main Methods:
- A study of 120 polymerase chain reaction (PCR)-confirmed COVID-19 patients was conducted.
- Data on ENT manifestations, other symptoms, and disease severity (categorized using CT scans) were collected and analyzed.
Main Results:
- The most frequent ENT symptoms included sore throat (30%), nasal congestion (28.3%), nasal obstruction (26.7%), and olfactory dysfunction (25%).
- Common non-ENT symptoms were fever (88.3%) and cough (63.3%).
- Sore throat, nasal congestion, and headache were the most prevalent ENT symptoms.
Conclusions:
- ENT manifestations are common in COVID-19 and should be considered in clinical suspicion.
- Sore throat, nasal congestion, and olfactory dysfunction are key ENT symptoms associated with COVID-19.
Abstract:
Introduction Coronavirus disease 2019 (COVID-19) has dramatically spread all over the world, crossing the borders of all countries. It is presented mainly by lower respiratory tract symptoms such as fever, cough, dyspnea, and chest tightness. However, COVID-19 causes different upper respiratory tract-related symptoms including nasal congestion, sore throat, and olfactory dysfunction. Objective To discuss different ear, nose and throat (ENT) manifestations in COVID-19-positive patients and their relation to other manifestations and to the severity of COVID-19. Methods We detected ENT manifestations in polymerase chain reaction (PCR)-confirmed positive COVID-19 patients at Zagazig Isolation Hospitals (Zagazig University hospitals, Zagazig Chest hospital, Al-Ahrar hospital, and Zagazig Fever hospital) with proportional allocation in the period from April 15 to June 15, 2020. All patients were subjected to full history taking and COVID-19 was categorized into 4 classes of severity after all patients underwent computed tomography (CT) of the chest. Afterwards, the collected data was analyzed and compared. Results Among the included 120 COVID-19 patients, the most frequent reported ENT manifestations were; sore throat (30%), nasal congestion (28.3%), nasal obstruction (26.7%), sneezing (26.6%), headache (25%), smell and taste dysfunction (25%), rhinorrhea (20%), upper respiratory tract infection (URTI) (15%), and tonsil enlargement (10%). The most common non-ENT manifestations were fever (88.3%), cough (63.3%), and dyspnea (45%). Conclusion Fever and cough are the dominant symptoms of COVID-19, but ENT manifestations for COVID-19 are common and should be a part of the suspected clinical criteria for COVID-19, particularly if the nasal examination was nonsignificant. The most common symptoms are sore throat, followed by nasal congestion and obstruction, headache, and lastly, olfactory dysfunction.
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