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Effect of multidimensional comprehensive intervention on medication compliance, social function and incidence of MACE

Yan Zhang1, Yuhua Yang2, Jinggang Xiao3

  • 1Department of Cardiovascular Medicine, Jinan People's Hospital Affiliated to Shandong First Medical University Jinan, Shandong, China.

American Journal of Translational Research
|August 11, 2021
PubMed

Insights

Multidimensional comprehensive intervention significantly improved medication adherence and social function in patients after percutaneous coronary intervention (PCI). This approach also reduced major adverse cardiovascular events (MACE), enhancing overall quality of life.

Area of Science:

  • Cardiology
  • Nursing Science
  • Public Health

Background:

  • Percutaneous coronary intervention (PCI) is a common procedure for coronary heart disease (CHD).
  • Post-PCI patients require comprehensive management to improve outcomes and prevent adverse events.
  • Medication compliance and social function are critical factors influencing long-term prognosis.

Purpose of the Study:

  • To evaluate the impact of a multidimensional comprehensive intervention on medication compliance.
  • To assess the effect of this intervention on social function and quality of life.
  • To determine the influence of the intervention on the incidence of major adverse cardiovascular events (MACE) in PCI patients.

Main Methods:

  • A study involving 98 patients with CHD who underwent PCI.
  • Patients were divided into a regular nursing intervention group (n=46) and a multidimensional comprehensive nursing intervention group (n=52).
  • Key outcomes measured included medication compliance, social function (using SDSS), quality of life, and MACE incidence.

Main Results:

  • The comprehensive group demonstrated significantly higher medication compliance rates (on time, correct dosage, adherence to schedule, no interruption) compared to the regular group (P < 0.05).
  • Social Disability Screening Schedule (SDSS) scores significantly decreased in both groups post-intervention, with greater improvement in the comprehensive group (P < 0.05).
  • The comprehensive group showed superior improvements in physiological, psychological, cognitive, emotional, and role functions, alongside total quality of life scores (P < 0.05), and a significantly lower incidence of MACE (P < 0.05).

Conclusions:

  • Multidimensional comprehensive intervention is effective in enhancing medication compliance among PCI patients.
  • This intervention strategy significantly improves social function and overall quality of life post-PCI.
  • Implementing multidimensional comprehensive care can effectively reduce the incidence of major adverse cardiovascular events (MACE) in patients undergoing PCI.
Abstract

Keywords:
Multidimensional comprehensive interventionadverse cardiovascular eventsmedication compliancepercutaneous coronary interventionsocial function

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