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Updated: Oct 25, 2025
Author Spotlight: A Reproductive Hysteroscopy Approach for Complete Endometrial Polyp Removal and Enhanced Endometrial Receptivity
Published on: August 2, 2024
Efficacy of hysteroscopic cold knife separation on intrauterine adhesions
Xia Jin1, Junliang Ye1, Li Zhang1
1Department of Obstetrics and Gynecology, Anhui Province Maternity and Child Health Hospital Hefei, Anhui Province, China.
Objective:
This research aimed to explore the efficacy of hysteroscopic cold knife separation in the treatment of intrauterine adhesions (IUA).
Methods:
Altogether 110 patients with IUA who were treated in our hospital were randomized into the observation group (n=55, hysteroscopic cold knife) and the control group (n=55, hysteroscopic electroacupuncture and collecting ring). This research compared the operation-related indexes (operation time, intraoperative blood loss, amount of distending media), IUA and menstrual flow, endometrial epithelization of the uterine wound, endometrial thickness one month after operation, recurrence and pregnancy rates one year after operation.
Results:
The operation time and intraoperative blood loss in the observation group were less than those in the control group (all P<0.05). After treatment, the total effective rate of IUA, menstrual flow and satisfaction rate of endometrial epithelization of the uterine wound in the observation group were higher than those in the control group, and the recurrence rate of the former one year after operation was lower (all P<0.05). One month after operation, the thickness of the endometrium in the observation group was clearly larger than that in the control group on the 11th and 13th day of menstruation (all P<0.05).
Conclusion:
Hysteroscopic cold knife separation can improve the efficacy of IUA and protect the endometrium.
