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Updated: Oct 25, 2025

Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies
Published on: December 1, 2023
Penile cancer after a tick bite: A possible association
Ognen Ivanovski1, Skender Saidi1, Bashkim Shabani1
1University Clinic of Urology, Medical Faculty, University "SS Cyril and Methodius," Skopje, Macedonia.
Abstract:
Penile cancer is a rare cancer in Western countries, but is more common in parts of the developing world. Usually, it is associated with older uncircumcised men who have a long-term phymotic preputium. Here, we report a case of penile cancer in a circumcised patient, occurring 3 months after a tick bite on the head of the penis. To the best of our knowledge, this is the first report that suggests a possible association between Lyme disease and occurrence of "de novo" penile cancer. Further studies are needed to confirm this hypothesis.
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