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Firstcase of pneumonia-parapneumonic effusion due to Trichoderma longibrachiatum

Vasiliki Epameinondas Georgakopoulou1, Despoina Melemeni2, Konstantinos Mantzouranis2

  • 1Pulmonology Department, Laiko General Hospital, Athens, Greece.

Idcases
|August 11, 2021
PubMed

Insights

Trichoderma longibrachiatum, a fungus, can cause severe infections in immunocompromised individuals. This report details the first case of pneumonia with parapneumonic effusion caused by this fungus in an elderly diabetic patient.

Area of Science:

  • Medical Mycology
  • Infectious Diseases

Background:

  • Trichoderma longibrachiatum is a fungus typically non-pathogenic to healthy individuals.
  • This fungus produces toxic peptides and extracellular proteases.
  • It is known to cause invasive infections in immunocompromised hosts.

Observation:

  • Trichoderma longibrachiatum has been implicated in various infections including lung, skin, sinus, and gastrointestinal infections.
  • The study reports the first case of pneumonia with parapneumonic effusion caused by Trichoderma longibrachiatum.
  • The affected patient was an elderly woman with diabetes mellitus.

Findings:

  • The case confirms Trichoderma longibrachiatum as a causative agent of pneumonia with parapneumonic effusion.
  • This highlights the potential pathogenicity of Trichoderma longibrachiatum in vulnerable populations.

Implications:

  • This case underscores the importance of considering fungal infections, such as Trichoderma longibrachiatum, in immunocompromised patients presenting with pneumonia.
  • Early diagnosis and appropriate antifungal treatment are crucial for managing such infections.
  • Further research into the virulence factors and clinical spectrum of Trichoderma longibrachiatum infections is warranted.
Keywords:
ADA, adenosine deaminaseALP, alkaline phosphataseALT, alanine transaminaseAST, aspartate aminotransferaseCRP, C-reactive proteinCT, computerized tomographyDiabetes mellitusESR, erythrocyte sedimentation rateFiO2, fraction of inspired oxygenFungal infectionGGT, gamma glutamyl transferaseHIV, human immunodeficiency virusHb, hemoglobinHt, hematocritLDH, serum lactate dehydrogenasePTLS, plateletsPleural effusionSG, specific gravityTSH, thyroid-stimulating hormoneTrichoderma longibrachiatumWBC, white blood cells

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