Related Experiment Video
Updated: Oct 25, 2025

07:01
An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
21.3K
Thymoma and Tuberculoma: Unexpected Coexistence
António Grilo Novais1, Diana Pinho Santos1, Mariana Conceição2
1Internal Medicine Department, Centro Hospitalar Tondela-Viseu, Portugal.
European Journal of Case Reports in Internal Medicine
|August 11, 2021
Summary
This case report highlights the rare co-occurrence of thymoma and tuberculosis (TB) in the thymus. Early diagnosis and biopsy are crucial for managing mediastinal masses, especially in TB-endemic areas.
Area of Science:
- Oncology
- Infectious Diseases
- Thoracic Surgery
Background:
- Mediastinal tumors are often found incidentally or present with symptoms.
- Thymoma is a tumor of the thymus gland.
- Tuberculosis (TB) can affect various organs, including the mediastinum.
Purpose of the Study:
- To report a rare case of simultaneous thymoma and thymus tuberculosis.
- To emphasize the importance of considering TB in the differential diagnosis of mediastinal masses.
Main Methods:
- Case report of a symptomatic woman.
- Diagnostic work-up including imaging and biopsy.
- Histopathological examination of the mediastinal mass.
Main Results:
- A B1 thymoma was diagnosed in conjunction with tuberculosis of the thymus.
- The patient presented with symptoms related to the mediastinal mass.
Conclusions:
- The co-occurrence of thymoma and thymic tuberculosis is exceptionally rare.
- Tuberculosis should be included in the differential diagnosis of mediastinal masses, particularly in endemic regions.
- Biopsy or resection of mediastinal masses is vital for accurate diagnosis.
Related Concept Videos
Pulmonary Tuberculosis III
539
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
539
Pulmonary Tuberculosis II
697
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
697
Pulmonary Tuberculosis IV
245
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
245
Pulmonary Tuberculosis I
426
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
426
Pulmonary Tuberculosis V
276
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
276
Tumor Immunotherapy
777
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
777

