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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
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Aggressive prostate cancer masquerading as acute prostatitis.

Kostantinos E Morris1, Dominic Grimberg, Rohith Arcot

  • 1Division of Urology, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA.

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Summary
This summary is machine-generated.

Prostatitis can elevate prostate-specific antigen (PSA) levels, sometimes masking prostate cancer. Extremely high PSA may indicate underlying cancer, warranting further investigation beyond prostatitis.

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Area of Science:

  • Urology
  • Oncology

Background:

  • Prostate-specific antigen (PSA) elevation is common in prostatitis.
  • Prostatitis can mimic or obscure other prostate conditions.

Observation:

  • A case presented of a man with undiagnosed prostate cancer.
  • Initial PSA levels exceeded 999.0 ng/mL.
  • The extreme PSA elevation was initially attributed solely to prostatitis.

Findings:

  • A greatly elevated PSA, even in the context of prostatitis, may signify underlying prostate cancer.
  • Clinicians should not automatically attribute all PSA elevations to prostatitis.

Implications:

  • Further investigation for prostate cancer is crucial when PSA levels are significantly high, even with suspected prostatitis.
  • This case highlights the importance of a thorough diagnostic approach to avoid missing prostate cancer diagnoses.