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Updated: Oct 25, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Monte Carlo calculation of beam quality correction factors in proton beams using FLUKA
Kilian-Simon Baumann1,2,3, Larissa Derksen2, Matthias Witt2,3
1University Medical Center Giessen-Marburg, Department of Radiotherapy and Radiooncology, Marburg, Germany.
Abstract:
Purpose.To provide Monte Carlo calculated beam quality correction factors (k) for monoenergetic proton beams using the Monte Carlo codefluka.Materials and methods.The Monte Carlo codeflukawas used to calculate the dose absorbed in a water-filled reference volume and the air-filled cavities of six plane-parallel and four cylindrical ionization chambers. The chambers were positioned at the entrance region of monoenergetic proton beams with energies between 60 and 250 MeV. Based on these dose values,fas well askfactors were calculated whilefQ0factors were taken from Andreoet al(2020Phys. Med. Biol.65095011).Results. kfactors calculated in this work were found to agree with experimentally determinedkfactors on the 1%-level, with only two exceptions with deviations of 1.4% and 1.9%. The comparison offfactors calculated usingflukawithffactors calculated using the Monte Carlo codesgeant4 andpenhshowed a general good agreement for low energies, while differences for higher energies were pronounced. For high energies, in most cases the Monte Carlo codesflukaandgeant4 lead to comparable results while theffactors calculated withpenhare larger.Conclusion.flukacan be used to calculatekfactors in clinical proton beams. The divergence of Monte Carlo calculatedkfactors for high energies suggests that the role of nuclear interaction models implemented in the different Monte Carlo codes needs to be investigated in more detail.
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