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Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies
Published on: August 11, 2023
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Relationship between anemia and oral cancer: a case-control study
Juliana Tomaz Sganzerla1, Gabriel Francisco Krueger1, Milene Castilhos de Oliveira1
1Universidade Luterana do Brasil - ULBRA, Department of Stomatology), Canoas, RS, Brazil.
Brazilian Oral Research
|August 11, 2021
Summary
Anemia is common in oral cancer patients, particularly normocytic anemia. Moderate to severe anemia may be linked to oral squamous cell carcinoma (OSCC) diagnosis.
Area of Science:
- Oncology
- Hematology
- Oral Medicine
Background:
- Anemia is a common comorbidity in various cancers.
- The relationship between anemia and oral cancer, specifically oral squamous cell carcinoma (OSCC), requires further investigation.
Purpose of the Study:
- To determine the prevalence, type, and severity of anemia at oral cancer diagnosis.
- To explore the association between anemia and the degree of tumor cell differentiation in oral cancer.
Main Methods:
- A case-control study involving 366 patients (70 with OSCC, 296 with benign oral lesions).
- Analysis of sociodemographic, behavioral, clinical variables, and complete blood count values.
- Statistical analysis using descriptive statistics and logistic regression.
Main Results:
- Anemia was present in 15.7% of oral cancer cases and 11.8% of controls.
- Normocytic anemia was the predominant type in both groups.
- Moderate to severe anemia showed a significant association with OSCC diagnosis (OR 6.49).
Conclusions:
- Anemia is a notable finding at the time of oral cancer diagnosis.
- Normocytic anemia is the most common type observed.
- More severe anemia may indicate a higher likelihood of oral squamous cell carcinoma.
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