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Updated: Jul 14, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
[Reconstruction of soft tissue defects of the lower extremities]
1Klinik für Plastische, Rekonstruktive, Ästhetische Chirurgie/Handchirurgie, Klinikum Lüdenscheid, Paulmannshöher Str. 14, 58515, Lüdenscheid, Deutschland.
Abstract:
A reliable reconstruction of soft tissue defects of the lower extremities especially in the distal third of the leg is still a special challenge for reconstructive surgeons. The possibility of salvaging the leg has to be evaluated in the setting of an interdisciplinary team and the timing of the operation(s) with respect to the safety of the patient and a systematic approach with the selection of a suitable flap have to be defined. Traditionally local muscle flaps or free flaps have been established for coverage of defects of the lower extremities. Recently perforator-based flaps have gained popularity for reconstruction of lower extremity defects. Furthermore, new surgical techniques and developments in association with the demographic change have led to a paradigm shift.

