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Culture-negative chronic hematogenous osteomyelitis in a two months old girl: a case report
Cheng-He Qin1, Rui Tao2, Ji-Wei Luo2
1Department of Orthopaedics and Traumatology, Southern Medical University Nanfang Hospital, No. 1838, Guangzhou Ave. North, Guangzhou, Guangdong, 510515, People's Republic of China. orthoqin@163.com.
Background:
Previous articles have focused on the diagnosis and treatment of acute hematogenous osteomyelitis. Here, we present a case of chronic hematogenous osteomyelitis in a 2-month-old girl. The diagnostic procedure was unusual and difficult due to negative culture results.
Case Presentation:
A girl aged 2 months and 23 days had fever and swelling in her right lower leg for 7 days. On the basis of her medical history, physical, and histological examination results; and radiologic and magnetic resonance imaging findings, a diagnosis of chronic osteomyelitis was made. The patient underwent surgical treatment and was discharged successfully. The patient showed good recovery and no sequelae at the 12-month follow-up.
Conclusion:
Hematogenous osteomyelitis in babyhood is different from that at any other age. Hematogenous osteomyelitis-related bone destruction in babyhood is more serious and occurs faster. The transition from acute hematogenous osteomyelitis to chronic hematogenous osteomyelitis takes only 7 days. To the best of our knowledge, this chronic hematogenous osteomyelitis patient is the youngest ever reported.

