Related Experiment Video
Updated: Oct 25, 2025

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
Published on: February 19, 2021
Cross-cutting lessons from the Decision-Maker Led Implementation Research initiative.
Arielle Mancuso1, Shahira Ahmed Malm2, Alyssa Sharkey3
1Alliance for Health Policy and Systems Research, WHO headquarters, Avenue Appia 20, 1211, Geneva, Switzerland. amancus3@jh.edu.
Decision-maker led research shows promise for improving vaccine implementation by embedding evidence into policy. Key enablers include research relevance and acceptability, while barriers involve unclear results and limited support.
Area of Science:
- Implementation Science
- Health Policy Research
- Vaccine Implementation Strategies
Background:
- Millions of children miss essential vaccines annually, primarily in low- and middle-income countries.
- Implementation research is vital for strengthening effective health interventions.
- Engaging decision-makers as Principal Investigators is a strategy to embed research into policy.
Purpose of the Study:
- To describe cross-cutting lessons from the "Decision-Maker Led Implementation Research" initiative.
- To understand and develop future use of the decision-maker led research strategy.
- To strengthen the implementation of proven-effective interventions, such as immunization.
Main Methods:
- Qualitative data collection including document review and in-depth interviews.
- Thematic content analysis of extracted documents.
- Analysis summarized results across 11 participating projects from the initiative.
Main Results:
- Seven enablers and five barriers to conducting decision-maker led research were identified.
- Key enablers included research relevance, acceptability, and integration.
- Key barriers included unclear results, limited planning/support, and the limited role of single studies.
Conclusions:
- Decision-maker led research is a promising strategy for embedding research into decision-making processes.
- This approach can increase research utilization to strengthen the implementation of interventions like immunization.
- Lessons learned can inform the future design and application of this research strategy.
Related Concept Videos
Decision Making: Traditional Method
First, a specific claim about the population parameter is decided based on the research question and is stated in a simple form. Further, an opposing statement to this claim is also stated. These statements can act as null and alternative hypotheses, out of which a null hypothesis would be a...
Impression Management Techniques III: Aligning Actions
Decision Making: P-value Method
First, a specific claim about the population parameter is proposed. The claim is based on the research question and is stated in a simple form. Further, an opposing statement to the claim is also stated. These statements can act as null and alternative hypotheses: a null hypothesis would be a neutral statement while the alternative hypothesis can...
Cognitive Learning
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Ethical Dilemmas II

