Paroxysmal Sympathetic Hyperactivity in a 73-Year-Old Female With Acute Myeloid Leukemia

Paroxysmal Sympathetic Hyperactivity (PSH) is a syndrome of recurrent exaggerated sympathetic responses in combination with motor features typically observed in the setting of traumatic brain injury and rarely seen without it. Here, we present a case of PSH in a 73-year-old female with acute myeloid leukemia (AML) without any brain injuries presenting with recurrent intermittent episodes of tachycardia, tachypnea, hypertension, fever, dystonia. These episodes resolved with clonidine and clonazepam thus confirming the diagnosis of PSH. PSH is an unusual and rare presentation in AML and not much literature has been reported.