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A search for new derivatives of chiral amino alcohols with an antiarrhythmic activity
M Eckstein1, K Tobiasz-Otrebska, D Kadłubowska
1Department of Chemical Technology of Drugs, Medical Academy, Kraków, Poland.
Abstract:
Twelve new (R) and (S) Schiff bases and twelve new (R) and (S) 2-benzylamino-1-butanols have been obtained. Pharmacological tests showed a weak antiarrhythmic and hypotensive activity of the screened chiral 2-benzylamino-1-butanols.